Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50296733'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50296733 (CHEMBL560069 | O-phenyl 1,4-diazabicyclo[3.2.2]non...) Show SMILES S=C(Oc1ccccc1)N1CCN2CCC1CC2 |TLB:1:9:14.13:16.17,(30.03,-23.84,;30.3,-25.36,;31.76,-25.89,;32.94,-24.89,;34.38,-25.42,;35.57,-24.43,;35.3,-22.91,;33.83,-22.38,;32.66,-23.38,;29.12,-26.36,;29.49,-27.84,;28.48,-27.11,;27.1,-27.18,;27.02,-25.47,;27.64,-24.32,;27.71,-25.73,;26.4,-26.44,;26.11,-27.89,)| Show InChI InChI=1S/C14H18N2OS/c18-14(17-13-4-2-1-3-5-13)16-11-10-15-8-6-12(16)7-9-15/h1-5,12H,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	749	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cells				Bioorg Med Chem Lett 19: 4747-51 (2009) Article DOI: 10.1016/j.bmcl.2009.06.059 BindingDB Entry DOI: 10.7270/Q21G0N69
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