Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50319679'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50319679 (1-(4-Piperidin-1-ylbutyl)-3-(4-pyridin-2-ylphenyl)...) Show SMILES O=C(NCCCCN1CCCCC1)Nc1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C21H28N4O/c26-21(23-14-4-7-17-25-15-5-1-6-16-25)24-19-11-9-18(10-12-19)20-8-2-3-13-22-20/h2-3,8-13H,1,4-7,14-17H2,(H2,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cells				J Med Chem 53: 4379-89 (2010) Article DOI: 10.1021/jm901692q BindingDB Entry DOI: 10.7270/Q2S46S4Q
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50319679 (1-(4-Piperidin-1-ylbutyl)-3-(4-pyridin-2-ylphenyl)...) Show SMILES O=C(NCCCCN1CCCCC1)Nc1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C21H28N4O/c26-21(23-14-4-7-17-25-15-5-1-6-16-25)24-19-11-9-18(10-12-19)20-8-2-3-13-22-20/h2-3,8-13H,1,4-7,14-17H2,(H2,23,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Targacept, Inc Curated by ChEMBL					Assay Description Agonist activity at alpha7 nAChR				J Med Chem 54: 7943-61 (2011) Article DOI: 10.1021/jm2007672 BindingDB Entry DOI: 10.7270/Q29P32QP
					More data for this Ligand-Target Pair