Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50399292'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50399292 (CHEMBL2180842) Show SMILES Fc1cncc(c1)-c1cc(NC(=O)CCCN2CCCCC2)[nH]n1 Show InChI InChI=1S/C17H22FN5O/c18-14-9-13(11-19-12-14)15-10-16(22-21-15)20-17(24)5-4-8-23-6-2-1-3-7-23/h9-12H,1-8H2,(H2,20,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha7 nAchR expressed in rat GH4C1 cell membranes				J Med Chem 55: 10277-81 (2012) Article DOI: 10.1021/jm3013568 BindingDB Entry DOI: 10.7270/Q2DJ5GRD
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50399292 (CHEMBL2180842) Show SMILES Fc1cncc(c1)-c1cc(NC(=O)CCCN2CCCCC2)[nH]n1 Show InChI InChI=1S/C17H22FN5O/c18-14-9-13(11-19-12-14)15-10-16(22-21-15)20-17(24)5-4-8-23-6-2-1-3-7-23/h9-12H,1-8H2,(H2,20,21,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Agonist activity at human alpha7 nAchR by patch clamp assay				J Med Chem 55: 10277-81 (2012) Article DOI: 10.1021/jm3013568 BindingDB Entry DOI: 10.7270/Q2DJ5GRD
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50399292 (CHEMBL2180842) Show SMILES Fc1cncc(c1)-c1cc(NC(=O)CCCN2CCCCC2)[nH]n1 Show InChI InChI=1S/C17H22FN5O/c18-14-9-13(11-19-12-14)15-10-16(22-21-15)20-17(24)5-4-8-23-6-2-1-3-7-23/h9-12H,1-8H2,(H2,20,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	740	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPR				J Med Chem 55: 10277-81 (2012) Article DOI: 10.1021/jm3013568 BindingDB Entry DOI: 10.7270/Q2DJ5GRD
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50399292 (CHEMBL2180842) Show SMILES Fc1cncc(c1)-c1cc(NC(=O)CCCN2CCCCC2)[nH]n1 Show InChI InChI=1S/C17H22FN5O/c18-14-9-13(11-19-12-14)15-10-16(22-21-15)20-17(24)5-4-8-23-6-2-1-3-7-23/h9-12H,1-8H2,(H2,20,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells by patch clamp assay				J Med Chem 55: 10277-81 (2012) Article DOI: 10.1021/jm3013568 BindingDB Entry DOI: 10.7270/Q2DJ5GRD
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50399292 (CHEMBL2180842) Show SMILES Fc1cncc(c1)-c1cc(NC(=O)CCCN2CCCCC2)[nH]n1 Show InChI InChI=1S/C17H22FN5O/c18-14-9-13(11-19-12-14)15-10-16(22-21-15)20-17(24)5-4-8-23-6-2-1-3-7-23/h9-12H,1-8H2,(H2,20,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	741	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPR				J Med Chem 55: 10277-81 (2012) Article DOI: 10.1021/jm3013568 BindingDB Entry DOI: 10.7270/Q2DJ5GRD
					More data for this Ligand-Target Pair