Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50399298'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50399298 (CHEMBL2180834) Show SMILES COc1ccc(cc1)-c1cc(NC(=O)CCCCCN2CCCN(CC2)C(C)=O)[nH]n1 Show InChI InChI=1S/C23H33N5O3/c1-18(29)28-14-6-13-27(15-16-28)12-5-3-4-7-23(30)24-22-17-21(25-26-22)19-8-10-20(31-2)11-9-19/h8-11,17H,3-7,12-16H2,1-2H3,(H2,24,25,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Siena Biotech SpA Curated by ChEMBL					Assay Description Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPR				J Med Chem 55: 10277-81 (2012) Article DOI: 10.1021/jm3013568 BindingDB Entry DOI: 10.7270/Q2DJ5GRD
					More data for this Ligand-Target Pair