Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50441948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50441948 (CHEMBL2440299) Show SMILES CCCNc1ncc(cc1C(=O)c1ccc(Cl)cc1)-c1ccc(OCC)cc1 Show InChI InChI=1S/C23H23ClN2O2/c1-3-13-25-23-21(22(27)17-5-9-19(24)10-6-17)14-18(15-26-23)16-7-11-20(12-8-16)28-4-2/h5-12,14-15H,3-4,13H2,1-2H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
University of California at Irvine Curated by ChEMBL					Assay Description Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...				J Med Chem 56: 8352-65 (2013) Article DOI: 10.1021/jm400704g BindingDB Entry DOI: 10.7270/Q29P3331
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