Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuropeptide FF receptor 2 (RAT) | BDBM50037573 ((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 15.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFF | J Med Chem 37: 3477-81 (1994) BindingDB Entry DOI: 10.7270/Q20R9NGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide FF receptor 2 (Homo sapiens (Human)) | BDBM50037573 ((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-1DMeNPFF from human NPFFR2 expressed in HEK293 cells incubated for 2 hrs by scintillation counting method | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00643 BindingDB Entry DOI: 10.7270/Q2SJ1QC8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide FF receptor 2 (RAT) | BDBM50037573 ((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-1DMeNPFF from rat NPFFR2 expressed in HEK293 cells incubated for 2 hrs by scintillation counting method | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00643 BindingDB Entry DOI: 10.7270/Q2SJ1QC8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide FF receptor 2 (Homo sapiens (Human)) | BDBM50037573 ((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 309 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cyclic cAMP accumulation | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00643 BindingDB Entry DOI: 10.7270/Q2SJ1QC8 | |||||||||||
More data for this Ligand-Target Pair |