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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 1' and Ligand = 'BDBM50109189'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50109189
PNG
(4-[3-(3-{3-[4-(3,4-Dichloro-phenyl)-piperazin-1-yl...)
Show SMILES CCOC(=O)C1=C(C)N=C(C)C(C1c1cccc(NC(=O)NCCCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)c1)C(=O)OC |c:5,t:8|
Show InChI InChI=1S/C32H39Cl2N5O5/c1-5-44-31(41)28-21(3)36-20(2)27(30(40)43-4)29(28)22-8-6-9-23(18-22)37-32(42)35-12-7-13-38-14-16-39(17-15-38)24-10-11-25(33)26(34)19-24/h6,8-11,18-19,27,29H,5,7,12-17H2,1-4H3,(H2,35,37,42)
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Similars
PubMed
 677n/an/an/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membrane

Bioorg Med Chem Lett 12: 379-82 (2002)


BindingDB Entry DOI: 10.7270/Q2DJ5DZ8
More data for this
Ligand-Target Pair