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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 1' and Ligand = 'BDBM50109191'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50109191
PNG
(5-Cyano-4-[3-(3-{3-[4-(2-methoxy-phenyl)-piperazin...)
Show SMILES COC(=O)C1=C(C)N=C(C)C(C#N)C1c1cccc(NC(=O)NCCCN2CCN(CC2)c2ccccc2OC)c1 |c:4,t:7|
Show InChI InChI=1S/C31H38N6O4/c1-21-25(20-32)29(28(22(2)34-21)30(38)41-4)23-9-7-10-24(19-23)35-31(39)33-13-8-14-36-15-17-37(18-16-36)26-11-5-6-12-27(26)40-3/h5-7,9-12,19,25,29H,8,13-18H2,1-4H3,(H2,33,35,39)
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Similars
PubMed
 684n/an/an/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membrane

Bioorg Med Chem Lett 12: 379-82 (2002)


BindingDB Entry DOI: 10.7270/Q2DJ5DZ8
More data for this
Ligand-Target Pair