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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 5' and Ligand = 'BDBM50084708'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50084708
PNG
(CHEMBL323892 | Naphthalene-2-sulfonic acid {4-[(6-...)
Show SMILES COc1ccc2C(Cc3cccnc3)C(CCc2c1)NCC1CC[C@H](CNS(=O)(=O)c2ccc3ccccc3c2)CC1 |wD:24.27,(3.47,-13.64,;4.79,-14.42,;6.13,-13.68,;6.16,-12.12,;7.5,-11.38,;8.81,-12.16,;10.15,-11.39,;10.18,-9.85,;8.87,-9.02,;7.52,-9.72,;6.22,-8.9,;6.28,-7.34,;7.66,-6.64,;8.97,-7.47,;11.51,-12.19,;11.48,-13.75,;10.12,-14.5,;8.81,-13.71,;7.47,-14.47,;12.86,-11.46,;14.16,-12.25,;15.52,-11.49,;15.56,-9.95,;16.9,-9.19,;18.21,-9.99,;19.57,-9.24,;20.88,-10.04,;22.42,-10.04,;22.01,-8.55,;23.95,-10.04,;23.19,-11.38,;22.39,-12.7,;23.15,-14.03,;24.68,-14.03,;25.45,-15.34,;26.98,-15.34,;27.75,-14.01,;26.98,-12.7,;25.45,-12.7,;24.71,-11.38,;18.18,-11.54,;16.84,-12.28,)|
Show InChI InChI=1S/C35H41N3O3S/c1-41-31-14-16-33-30(20-31)13-17-35(34(33)19-27-5-4-18-36-22-27)37-23-25-8-10-26(11-9-25)24-38-42(39,40)32-15-12-28-6-2-3-7-29(28)21-32/h2-7,12,14-16,18,20-22,25-26,34-35,37-38H,8-11,13,17,19,23-24H2,1H3/t25?,26-,34?,35?
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n/an/a 337n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.

J Med Chem 43: 346-50 (2000)


BindingDB Entry DOI: 10.7270/Q2XK8DS5
More data for this
Ligand-Target Pair