Found 2 hits Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 5' and Ligand = 'BDBM50301656' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301656
(CHEMBL567527 | trans-1'-oxo-N-(5-phenylpyrimidin-2...)Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:18.23,wD:15.16,(28.35,-35.04,;29.11,-36.37,;30.65,-36.38,;31.49,-37.67,;30.78,-39.03,;31.62,-40.33,;33.16,-40.25,;33.86,-38.87,;33.02,-37.58,;34,-41.54,;33.29,-42.91,;34.13,-44.2,;35.67,-44.13,;36.37,-42.75,;35.53,-41.46,;28.34,-37.71,;26.8,-37.71,;26.03,-39.04,;26.8,-40.37,;28.34,-40.37,;29.11,-39.04,;27.72,-41.62,;26.81,-42.88,;27.29,-44.34,;25.33,-42.4,;24,-43.17,;22.67,-42.4,;22.67,-40.86,;24,-40.09,;25.33,-40.85,)| Show InChI InChI=1S/C23H20N4O3/c28-20(27-22-25-12-17(13-26-22)15-4-2-1-3-5-15)16-6-9-23(10-7-16)19-14-24-11-8-18(19)21(29)30-23/h1-5,8,11-14,16H,6-7,9-10H2,(H,25,26,27,28)/t16-,23- | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells |
Bioorg Med Chem Lett 19: 5436-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.103 BindingDB Entry DOI: 10.7270/Q27D2V6Q |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50301656
(CHEMBL567527 | trans-1'-oxo-N-(5-phenylpyrimidin-2...)Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:18.23,wD:15.16,(28.35,-35.04,;29.11,-36.37,;30.65,-36.38,;31.49,-37.67,;30.78,-39.03,;31.62,-40.33,;33.16,-40.25,;33.86,-38.87,;33.02,-37.58,;34,-41.54,;33.29,-42.91,;34.13,-44.2,;35.67,-44.13,;36.37,-42.75,;35.53,-41.46,;28.34,-37.71,;26.8,-37.71,;26.03,-39.04,;26.8,-40.37,;28.34,-40.37,;29.11,-39.04,;27.72,-41.62,;26.81,-42.88,;27.29,-44.34,;25.33,-42.4,;24,-43.17,;22.67,-42.4,;22.67,-40.86,;24,-40.09,;25.33,-40.85,)| Show InChI InChI=1S/C23H20N4O3/c28-20(27-22-25-12-17(13-26-22)15-4-2-1-3-5-15)16-6-9-23(10-7-16)19-14-24-11-8-18(19)21(29)30-23/h1-5,8,11-14,16H,6-7,9-10H2,(H,25,26,27,28)/t16-,23- | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor |
Bioorg Med Chem 17: 6971-82 (2009)
Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62 |
More data for this Ligand-Target Pair | |