Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neutrophil collagenase' and Ligand = 'BDBM50077373'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50077373 ((R)-7-Amino-2-(4'-fluoro-biphenyl-4-sulfonyl)-1,2,...) Show SMILES Nc1ccc2C[C@@H](N(Cc2c1)S(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1)C(=O)NO Show InChI InChI=1S/C22H20FN3O4S/c23-18-6-1-14(2-7-18)15-4-9-20(10-5-15)31(29,30)26-13-17-11-19(24)8-3-16(17)12-21(26)22(27)25-28/h1-11,21,28H,12-13,24H2,(H,25,27)/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Marion Roussel Curated by ChEMBL					Assay Description Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]				J Med Chem 42: 1908-20 (1999) Article DOI: 10.1021/jm980631s BindingDB Entry DOI: 10.7270/Q2251JV5
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