Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neutrophil collagenase' and Ligand = 'BDBM50077385'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50077385 (CHEMBL301626 | [(R)-2-(4'-Fluoro-biphenyl-4-sulfon...) Show SMILES OC(=O)C(=O)[C@H]1Cc2ccccc2CN1S(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H18FNO5S/c24-19-9-5-15(6-10-19)16-7-11-20(12-8-16)31(29,30)25-14-18-4-2-1-3-17(18)13-21(25)22(26)23(27)28/h1-12,21H,13-14H2,(H,27,28)/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Marion Roussel Curated by ChEMBL					Assay Description Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]				J Med Chem 42: 1908-20 (1999) Article DOI: 10.1021/jm980631s BindingDB Entry DOI: 10.7270/Q2251JV5
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