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Found 1 hit Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM50023532'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil elastase


(Homo sapiens (Human))		BDBM50023532
PNG
(2,2-Dimethyl-propionic acid 4-(4-hydroxy-benzoyl)-...)
Show SMILES CC(C)(C)C(=O)Oc1ccc(cc1)C(=O)c1ccc(O)cc1
Show InChI InChI=1S/C18H18O4/c1-18(2,3)17(21)22-15-10-6-13(7-11-15)16(20)12-4-8-14(19)9-5-12/h4-11,19H,1-3H3
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MMDB

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n/an/a 2.70E+3n/an/an/an/an/an/a



Searle Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against human leukocyte elastase at 10e-6 M

J Med Chem 31: 1052-61 (1988)


BindingDB Entry DOI: 10.7270/Q2PC31DJ
More data for this
Ligand-Target Pair