Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM50286682'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50286682 ((2S,2aR)-2-Methoxy-3,3-dioxo-7-phenyl-2,2a,3,4-tet...) Show SMILES CO[C@@H]1[C@@H]2N(C1=O)c1c(CS2(=O)=O)csc1-c1ccccc1 Show InChI InChI=1S/C15H13NO4S2/c1-20-12-14(17)16-11-10(8-22(18,19)15(12)16)7-21-13(11)9-5-3-2-4-6-9/h2-7,12,15H,8H2,1H3/t12-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	n/a	n/a	270	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human leukocyte elastase (HLE) expressed as second order inhibition rate constant				Bioorg Med Chem Lett 5: 691-694 (1995) Article DOI: 10.1016/0960-894X(95)00095-B BindingDB Entry DOI: 10.7270/Q2Q2407G
					More data for this Ligand-Target Pair