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Found 1 hit Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM50291938'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil elastase


(Homo sapiens (Human))		BDBM50291938
PNG
(2,2-Dimethyl-propionic acid (4S,7S)-2-(2,2-dimethy...)
Show SMILES CO[C@@H]1C2N(C1=O)C(C(=O)C(C)(C)C)=C(C)[C@@H](OC(=O)C(C)(C)C)S2(=O)=O |t:14|
Show InChI InChI=1S/C18H27NO7S/c1-9-10(12(20)17(2,3)4)19-13(21)11(25-8)14(19)27(23,24)15(9)26-16(22)18(5,6)7/h11,14-15H,1-8H3/t11-,14?,15-/m0/s1
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PubMed
n/an/an/an/an/an/a 1.50E+6n/an/a



Pharmacia Farmitalia Carlo Erba

Curated by ChEMBL


Assay Description
Tested for the rate constant against Human Leukocyte Elastase (HLE) inactivation

J Med Chem 37: 4003-19 (1994)


BindingDB Entry DOI: 10.7270/Q2T43S5B
More data for this
Ligand-Target Pair