Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM180067'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM180067 (US9676721, 17 1-[(4-{[4-chloro-3-(trifluoromethyl)...) Show SMILES FC(F)(F)c1cc(ccc1Cl)S(=O)(=O)c1ccc(CNC(Nc2ccncc2)=NC#N)cc1 |w:28.30| Show InChI InChI=1S/C21H15ClF3N5O2S/c22-19-6-5-17(11-18(19)21(23,24)25)33(31,32)16-3-1-14(2-4-16)12-28-20(29-13-26)30-15-7-9-27-10-8-15/h1-11H,12H2,(H2,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9676721 (2017) BindingDB Entry DOI: 10.7270/Q2VD6WMM
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