Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM180915'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM180915 (US9676721, 21 1-{2-[4-(benzenesulfonyl)phenyl]ethy...) Show SMILES O=S(=O)(c1ccccc1)c1ccc(CCN\C(Nc2ccncc2)=N/C#N)cc1 Show InChI InChI=1S/C21H19N5O2S/c22-16-25-21(26-18-11-13-23-14-12-18)24-15-10-17-6-8-20(9-7-17)29(27,28)19-4-2-1-3-5-19/h1-9,11-14H,10,15H2,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9676721 (2017) BindingDB Entry DOI: 10.7270/Q2VD6WMM
					More data for this Ligand-Target Pair