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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM50168029'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nicotinamide phosphoribosyltransferase


(Homo sapiens (Human))		BDBM50168029
PNG
(CHEMBL3799664)
Show SMILES O=C(N1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)c1cc(n[nH]1)-c1cccnc1
Show InChI InChI=1S/C22H20N6O2/c29-21(19-12-15-4-1-2-6-17(15)24-19)27-8-10-28(11-9-27)22(30)20-13-18(25-26-20)16-5-3-7-23-14-16/h1-7,12-14,24H,8-11H2,(H,25,26)
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MMDB

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Article
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



Charles River Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human NAMPT using NAM as substrate assessed as NMN formation preincubated for 5 mins followed by substrate addition measured after 15 m...

Bioorg Med Chem Lett 26: 2920-2926 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.039
BindingDB Entry DOI: 10.7270/Q2RR215F
More data for this
Ligand-Target Pair