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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM50168034'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nicotinamide phosphoribosyltransferase


(Homo sapiens (Human))		BDBM50168034
PNG
(CHEMBL3797738)
Show SMILES O=C(Nc1ccc(cc1)-c1nnc2CCCCCn12)\C=C\c1cccnc1
Show InChI InChI=1S/C21H21N5O/c27-20(12-7-16-5-4-13-22-15-16)23-18-10-8-17(9-11-18)21-25-24-19-6-2-1-3-14-26(19)21/h4-5,7-13,15H,1-3,6,14H2,(H,23,27)/b12-7+
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Article
PubMed
n/an/a 670n/an/an/an/an/an/a



Charles River Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human NAMPT using NAM as substrate assessed as NMN formation preincubated for 5 mins followed by substrate addition measured after 15 m...

Bioorg Med Chem Lett 26: 2920-2926 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.039
BindingDB Entry DOI: 10.7270/Q2RR215F
More data for this
Ligand-Target Pair