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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM572939'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nicotinamide phosphoribosyltransferase


(Homo sapiens (Human))
BDBM572939
PNG
(1-[4-(3-Iodo-benzenesulfonyl)-phenyl]-3-(1H-pyrazo...)
Show SMILES Ic1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)NCc2cn[nH]c2)cc1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<100n/an/an/an/a


TBA

Assay Description
NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2M048P0
More data for this
Ligand-Target Pair