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Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, brain' and Ligand = 'BDBM50348719'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM50348719
PNG
(CHEMBL1801488)
Show SMILES Fc1ccc2c(Cn3c(nc4ccccc34)C3CCCC3)cc(=O)[nH]c2c1F
Show InChI InChI=1S/C22H19F2N3O/c23-16-10-9-15-14(11-19(28)26-21(15)20(16)24)12-27-18-8-4-3-7-17(18)25-22(27)13-5-1-2-6-13/h3-4,7-11,13H,1-2,5-6,12H2,(H,26,28)
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Article
PubMed
n/an/an/an/a 770n/an/an/an/a



Kalypsys, Inc

Curated by ChEMBL


Assay Description
Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...

J Med Chem 53: 7739-55 (2010)


Article DOI: 10.1021/jm100828n
BindingDB Entry DOI: 10.7270/Q29Z9584
More data for this
Ligand-Target Pair