Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, endothelial' and Ligand = 'BDBM50523378'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, endothelial (Rattus norvegicus)	BDBM50523378 (CHEMBL4556372) Show SMILES Cl.Cl.COc1ccc2nc3CCCCc3c(NCCCNC(=O)[C@@H](N)Cc3c[nH]c4ccccc34)c2c1 |r| Show InChI InChI=1S/C28H33N5O2.2ClH/c1-35-19-11-12-26-22(16-19)27(21-8-3-5-10-25(21)33-26)30-13-6-14-31-28(34)23(29)15-18-17-32-24-9-4-2-7-20(18)24;;/h2,4,7,9,11-12,16-17,23,32H,3,5-6,8,10,13-15,29H2,1H3,(H,30,33)(H,31,34);2*1H/t23-;;/m0../s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hradec Kralove Curated by ChEMBL					Assay Description Inhibition of nNOS in Wistar rat cortical homogenates incubated for 30 mins				Eur J Med Chem 168: 491-514 (2019) Article DOI: 10.1016/j.ejmech.2019.02.021 BindingDB Entry DOI: 10.7270/Q2RV0S3X
					More data for this Ligand-Target Pair