BindingDB PrimarySearch

Found 4 hits Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, inducible' and Ligand = 'BDBM50049254'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50049254 ((2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic ...) Show SMILES CN(CCC[C@H](N)C(O)=O)C(N)=N Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity towards inducible nitric oxide synthase				Bioorg Med Chem Lett 15: 3934-41 (2005) Article DOI: 10.1016/j.bmcl.2005.05.088 BindingDB Entry DOI: 10.7270/Q2V69KBC
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50049254 ((2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic ...) Show SMILES CN(CCC[C@H](N)C(O)=O)C(N)=N Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human inducible nitric oxide synthase				J Med Chem 39: 669-72 (1996) Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M
G. D. Searle Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50049254 ((2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic ...) Show SMILES CN(CCC[C@H](N)C(O)=O)C(N)=N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Haute-Alsace Curated by ChEMBL					Assay Description Compound was evaluated for inhibitory activity against iNOS obtained from RAW 264.7 cells.				Bioorg Med Chem Lett 8: 2961-6 (1999) Article DOI: 10.1016/S0960-894X(98)00532-0 BindingDB Entry DOI: 10.7270/Q2DZ07G5
Université de Haute-Alsace Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50049254 ((2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic ...) Show SMILES CN(CCC[C@H](N)C(O)=O)C(N)=N Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of human recombinant iNOS by griess assay				Bioorg Med Chem 16: 2305-12 (2008) Article DOI: 10.1016/j.bmc.2007.11.066 BindingDB Entry DOI: 10.7270/Q2KW5GXN
Christian-Albrechts-University of Kiel Curated by ChEMBL					More data for this Ligand-Target Pair