Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM469815'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM469815 (CIS-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo...) Show SMILES CN(C)[C@]1(CC[C@]2(CN(CC(=O)Nc3ccc(C)nc3)C(=O)N2CC2CCC2)CC1)c1ccccc1 |r,wU:3.2,6.23,(14.12,24.55,;15.21,23.47,;16.54,24.24,;14.81,21.98,;14.81,20.44,;13.47,19.67,;12.14,20.44,;10.73,21.06,;9.7,19.92,;8.22,20.32,;7.13,19.23,;7.53,17.74,;5.64,19.63,;4.55,18.54,;4.95,17.05,;3.86,15.96,;2.37,16.36,;1.28,15.27,;1.97,17.85,;3.06,18.94,;10.47,18.59,;10.07,17.1,;11.98,18.91,;13.07,17.82,;12.67,16.33,;11.34,15.56,;12.11,14.23,;13.44,15,;12.14,21.98,;13.47,22.75,;16.3,21.58,;16.69,20.09,;18.18,19.69,;19.27,20.78,;18.87,22.27,;17.38,22.67,)| Show InChI InChI=1S/C29H39N5O2/c1-22-12-13-25(18-30-22)31-26(35)20-33-21-28(34(27(33)36)19-23-8-7-9-23)14-16-29(17-15-28,32(2)3)24-10-5-4-6-11-24/h4-6,10-13,18,23H,7-9,14-17,19-21H2,1-3H3,(H,31,35)/t28-,29+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GRÜNENTHAL GMBH US Patent					Assay Description The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...				US Patent US10807989 (2020) BindingDB Entry DOI: 10.7270/Q2222XTM
					More data for this Ligand-Target Pair