Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM469858'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM469858 (CIS-N-(4-Cyano-5-methylsulfanyl-1H-pyrazol-3-yl)-2...) Show SMILES CSc1[nH]nc(NC(=O)CN2C[C@]3(CC[C@@](CC3)(N(C)C)c3ccccc3)N(CC3CCC3)C2=O)c1C#N |r,wU:15.18,12.28,(19.85,-25.97,;18.31,-25.97,;17.54,-27.3,;18.17,-28.71,;17.02,-29.74,;15.69,-28.97,;14.2,-29.37,;13.11,-28.28,;13.51,-26.79,;11.62,-28.68,;10.54,-27.59,;9.07,-28.06,;8.17,-26.82,;7.4,-25.48,;5.86,-25.48,;5.09,-26.82,;5.86,-28.15,;7.4,-28.15,;4,-27.91,;2.51,-27.51,;4.39,-29.39,;4,-25.73,;4.39,-24.24,;3.31,-23.15,;1.82,-23.55,;1.42,-25.04,;2.51,-26.13,;9.07,-25.57,;8.67,-24.08,;9.76,-22.99,;11.3,-22.99,;11.3,-21.45,;9.76,-21.45,;10.54,-26.05,;11.62,-24.96,;16.01,-27.46,;15.24,-26.13,;13.7,-26.13,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GRÜNENTHAL GMBH US Patent					Assay Description The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...				US Patent US10807989 (2020) BindingDB Entry DOI: 10.7270/Q2222XTM
					More data for this Ligand-Target Pair