BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50173278'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))
BDBM50173278
PNG
(CHEMBL198322 | methyl 2-[2-oxo-1'-(4-phenylbenzyl)...)
Show SMILES COC(=O)CN1C(=O)C2(CCN(Cc3ccc(cc3)-c3ccccc3)CC2)c2ccccc12
Show InChI InChI=1S/C28H28N2O3/c1-33-26(31)20-30-25-10-6-5-9-24(25)28(27(30)32)15-17-29(18-16-28)19-21-11-13-23(14-12-21)22-7-3-2-4-8-22/h2-14H,15-20H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...


Bioorg Med Chem Lett 15: 5022-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.009
BindingDB Entry DOI: 10.7270/Q2RF5TKC
More data for this
Ligand-Target Pair