BindingDB PrimarySearch

Found 4 hits Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50274449'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nociceptin receptor (RAT)	BDBM50274449 (CHEMBL505874 \| FGGFTGARKSARKRKNQ) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells				Bioorg Med Chem 16: 9261-7 (2008) Article DOI: 10.1016/j.bmc.2008.09.014 BindingDB Entry DOI: 10.7270/Q2MC90XH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (RAT)	BDBM50274449 (CHEMBL505874 \| FGGFTGARKSARKRKNQ) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells by competitive binding assay				Bioorg Med Chem 17: 5683-7 (2009) Article DOI: 10.1016/j.bmc.2009.06.015 BindingDB Entry DOI: 10.7270/Q2GB2435
Kyushu University Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (RAT)	BDBM50274449 (CHEMBL505874 \| FGGFTGARKSARKRKNQ) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem 16: 9261-7 (2008) Article DOI: 10.1016/j.bmc.2008.09.014 BindingDB Entry DOI: 10.7270/Q2MC90XH
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (RAT)	BDBM50274449 (CHEMBL505874 \| FGGFTGARKSARKRKNQ) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Agonist activity at rat ORL1 receptor expressed in african green monkey COS7 cells assessed as stimulation of [35S]GTPgammaS binding by radioligand r...				Bioorg Med Chem 17: 5683-7 (2009) Article DOI: 10.1016/j.bmc.2009.06.015 BindingDB Entry DOI: 10.7270/Q2GB2435
Kyushu University Curated by ChEMBL					More data for this Ligand-Target Pair