Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM125914'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM125914 (US8765727, 17) Show SMILES Nc1ccc2CNc3nc(Nc4cncc(CCc1c2)c4)ncc3Cl Show InChI InChI=1S/C18H17ClN6/c19-15-10-23-18-24-14-6-12(7-21-9-14)1-3-13-5-11(2-4-16(13)20)8-22-17(15)25-18/h2,4-7,9-10H,1,3,8,20H2,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	386	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...				US Patent US8765727 (2014) BindingDB Entry DOI: 10.7270/Q2FQ9V87
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