BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2 [575-869]' and Ligand = 'BDBM500288'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 [575-869] (Homo sapiens (Human))	BDBM500288 (US11021475, Example 52 \| US11021475, Example 67 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	n/a	n/a	6.53	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...				US Patent US11021475 (2021) BindingDB Entry DOI: 10.7270/Q2S75KGC
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Non-receptor tyrosine-protein kinase TYK2 [575-869] (Homo sapiens (Human))	BDBM500288 (US11021475, Example 52 \| US11021475, Example 67 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	n/a	n/a	5.13	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...				US Patent US11021475 (2021) BindingDB Entry DOI: 10.7270/Q2S75KGC
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)