Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2 [871-1187]' and Ligand = 'BDBM348929'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 [871-1187] (Homo sapiens (Human))	BDBM348929 (4-(2- (cyclopropanecarboxamido)- [1,2,4]triazolo[1...) Show SMILES O=C(Nc1nc2cccc(-c3ccc(cc3)C(=O)Nc3ccccc3)n2n1)C1CC1 Show InChI InChI=1S/C23H19N5O2/c29-21(24-18-5-2-1-3-6-18)16-11-9-15(10-12-16)19-7-4-8-20-25-23(27-28(19)20)26-22(30)17-13-14-17/h1-12,17H,13-14H2,(H,24,29)(H,26,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description Recombinant human TYK2 catalytic domain (amino acids 871-1187; catalog number 08-147) was purchased from Carna biosciences. 5 ng of TYK2 was incubate...				US Patent US10206907 (2019) BindingDB Entry DOI: 10.7270/Q23J3G3B
					More data for this Ligand-Target Pair