Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Non-receptor tyrosine-protein kinase TYK2 [886-1187] (Homo sapiens (Human)) | BDBM127751 (US10251889, Example 124 | US10758542, Example 124 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma, Inc. US Patent | Assay Description Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c... | US Patent US9782415 (2017) BindingDB Entry DOI: 10.7270/Q2P84F0G | |||||||||||
More data for this Ligand-Target Pair |