Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nuclear factor NF-kappa-B p105 subunit' and Ligand = 'BDBM191749'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human))	BDBM191749 (US9187397, 2 | US9187397, 6a) Show SMILES COc1cc(\C=C\C(\O)=C(/C)C(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O Show InChI InChI=1S/C22H22O6/c1-14(17(23)8-4-15-6-10-19(25)21(12-15)27-2)18(24)9-5-16-7-11-20(26)22(13-16)28-3/h4-13,23,25-26H,1-3H3/b8-4+,9-5+,17-14-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
STC.UNM US Patent					Assay Description The 293T/NF-κB-luc cells were re-plated 24 hr prior to treatment, into 24-well cell culture plates in media without hygromycin, to prevent it from...				US Patent US9187397 (2015) BindingDB Entry DOI: 10.7270/Q2Q52NF9
					More data for this Ligand-Target Pair
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human))	BDBM191749 (US9187397, 2 | US9187397, 6a) Show SMILES COc1cc(\C=C\C(\O)=C(/C)C(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O Show InChI InChI=1S/C22H22O6/c1-14(17(23)8-4-15-6-10-19(25)21(12-15)27-2)18(24)9-5-16-7-11-20(26)22(13-16)28-3/h4-13,23,25-26H,1-3H3/b8-4+,9-5+,17-14-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
STC.UNM US Patent					Assay Description TRAP Assay: The first procedure called for antioxidant activity to be measured as the ability of the analogs to react with the pre-formed radical mon...				US Patent US9187397 (2015) BindingDB Entry DOI: 10.7270/Q2Q52NF9
					More data for this Ligand-Target Pair