Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear factor NF-kappa-B p105 subunit' and Ligand = 'BDBM191763'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human))	BDBM191763 (US10669227, Compound Curcumin | US11608309, Compou...) Show SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(CO)c2)ccc1O Show InChI InChI=1S/C21H20O6/c1-27-21-11-15(5-9-20(21)26)3-7-18(24)12-17(23)6-2-14-4-8-19(25)16(10-14)13-22/h2-11,22,25-26H,12-13H2,1H3/b6-2+,7-3+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
STC.UNM US Patent					Assay Description The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...				US Patent US9187397 (2015) BindingDB Entry DOI: 10.7270/Q2Q52NF9
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