Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nuclear factor NF-kappa-B p105 subunit' and Ligand = 'BDBM367266'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human))	BDBM367266 (US10226464, Compound 34) Show SMILES CC(C)(C)CCOc1cc2oc3nc(=O)[nH]c(=O)c3cc2cc1F Show InChI InChI=1S/C17H17FN2O4/c1-17(2,3)4-5-23-13-8-12-9(7-11(13)18)6-10-14(21)19-16(22)20-15(10)24-12/h6-8H,4-5H2,1-3H3,(H,19,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DNA binding reaction (20 μL) was carried out in 1×DNA Binding Buffer (10 mM Tris, 40 mM NaCl, 1 mM EDTA, 4% glycerol) with 10 nM c-Rel protein a...				Bioorg Med Chem Lett 17: 5384-9 (2007) BindingDB Entry DOI: 10.7270/Q2028TVG
					More data for this Ligand-Target Pair
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human))	BDBM367266 (US10226464, Compound 34) Show SMILES CC(C)(C)CCOc1cc2oc3nc(=O)[nH]c(=O)c3cc2cc1F Show InChI InChI=1S/C17H17FN2O4/c1-17(2,3)4-5-23-13-8-12-9(7-11(13)18)6-10-14(21)19-16(22)20-15(10)24-12/h6-8H,4-5H2,1-3H3,(H,19,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description NFκB/Jurkat/GFP transcriptional reporter cell line was obtained from SBI System Biosciences. NF-κB/Jurkat/GFP™ Reporter cells (5×105 cells)...				Bioorg Med Chem Lett 17: 5384-9 (2007) BindingDB Entry DOI: 10.7270/Q2028TVG
					More data for this Ligand-Target Pair