Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM285768'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285768 (US10080744, Example 3/35) Show SMILES C[C@H](NC(=O)c1cc(cc(c1)C1(C)CC1)-c1sc(nc1CC1CCC1)-c1nnc(CC(C)(C)OC=O)o1)C(F)(F)F |r| Show InChI InChI=1S/C29H33F3N4O4S/c1-16(29(30,31)32)33-24(38)19-11-18(12-20(13-19)28(4)8-9-28)23-21(10-17-6-5-7-17)34-26(41-23)25-36-35-22(40-25)14-27(2,3)39-15-37/h11-13,15-17H,5-10,14H2,1-4H3,(H,33,38)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285768 (US10080744, Example 3/35) Show SMILES C[C@H](NC(=O)c1cc(cc(c1)C1(C)CC1)-c1sc(nc1CC1CCC1)-c1nnc(CC(C)(C)OC=O)o1)C(F)(F)F |r| Show InChI InChI=1S/C29H33F3N4O4S/c1-16(29(30,31)32)33-24(38)19-11-18(12-20(13-19)28(4)8-9-28)23-21(10-17-6-5-7-17)34-26(41-23)25-36-35-22(40-25)14-27(2,3)39-15-37/h11-13,15-17H,5-10,14H2,1-4H3,(H,33,38)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description For the RORγt construct used in the ThermoFluor assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR&...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair