Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM292745'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM292745 (US10106501, Example B-22) Show SMILES Cc1cc(cc2n(C)c(Cc3c(Cl)ncc(C(=O)N4CCC(CC(O)=O)CC4)c3Cl)cc12)C(F)(F)F Show InChI InChI=1S/C25H24Cl2F3N3O3/c1-13-7-15(25(28,29)30)9-20-17(13)10-16(32(20)2)11-18-22(26)19(12-31-23(18)27)24(36)33-5-3-14(4-6-33)8-21(34)35/h7,9-10,12,14H,3-6,8,11H2,1-2H3,(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...				US Patent US10106501 (2018) BindingDB Entry DOI: 10.7270/Q2G44SBV
					More data for this Ligand-Target Pair