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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM365690'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM365690
PNG
(US9868748, I-B13)
Show SMILES CC(C)[C@@H]1N(Cc2sc(NC(=O)Cc3ccc(cc3)S(C)(=O)=O)nc12)[C@H](C)c1ccc(nc1C)C(F)(F)F
Show InChI InChI=1S/C26H29F3N4O3S2/c1-14(2)24-23-20(13-33(24)16(4)19-10-11-21(26(27,28)29)30-15(19)3)37-25(32-23)31-22(34)12-17-6-8-18(9-7-17)38(5,35)36/h6-11,14,16,24H,12-13H2,1-5H3,(H,31,32,34)/t16-,24+/m1/s1
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US Patent
<100n/an/an/an/an/an/an/an/a



Novartis Pharmaceuticals



Assay Description
Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...

J Med Chem 45: 1399-401 (2002)


BindingDB Entry DOI: 10.7270/Q2W95CHZ
More data for this
Ligand-Target Pair