Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50044246'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Mus musculus)	BDBM50044246 (CHEMBL3314042) Show SMILES [H][C@@]12C[C@]1([H])C[C@@H](C2)Oc1cc(ccc1N(C)C(=O)c1c(F)cccc1Cl)-c1cc(ccc1Cl)C(N)=O |r| Show InChI InChI=1S/C27H23Cl2FN2O3/c1-32(27(34)25-21(29)3-2-4-22(25)30)23-8-6-14(19-12-15(26(31)33)5-7-20(19)28)13-24(23)35-18-10-16-9-17(16)11-18/h2-8,12-13,16-18H,9-11H2,1H3,(H2,31,33)/t16-,17+,18+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 production				J Med Chem 57: 5871-92 (2014) Article DOI: 10.1021/jm401901d BindingDB Entry DOI: 10.7270/Q2M0473Z
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50044246 (CHEMBL3314042) Show SMILES [H][C@@]12C[C@]1([H])C[C@@H](C2)Oc1cc(ccc1N(C)C(=O)c1c(F)cccc1Cl)-c1cc(ccc1Cl)C(N)=O |r| Show InChI InChI=1S/C27H23Cl2FN2O3/c1-32(27(34)25-21(29)3-2-4-22(25)30)23-8-6-14(19-12-15(26(31)33)5-7-20(19)28)13-24(23)35-18-10-16-9-17(16)11-18/h2-8,12-13,16-18H,9-11H2,1H3,(H2,31,33)/t16-,17+,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inverse agonist activity at human RoRc-LBD expressed in cells assessed as TRAP-220 coactivator peptide recruitment				J Med Chem 57: 5871-92 (2014) Article DOI: 10.1021/jm401901d BindingDB Entry DOI: 10.7270/Q2M0473Z
					More data for this Ligand-Target Pair