Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma [262-507]' and Ligand = 'BDBM253235'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma [262-507] (Homo sapiens (Human))	BDBM253235 (US9458171, 195) Show SMILES Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)c1ccc2C(=O)NS(=O)(=O)c2c1)c1ccc(cc1)C(OCc1c(F)cccc1F)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C34H23F9N2O7S2/c35-22-9-11-23(12-10-22)53(48,49)31(14-15-45(18-31)30(47)19-4-13-24-28(16-19)54(50,51)44-29(24)46)20-5-7-21(8-6-20)32(33(38,39)40,34(41,42)43)52-17-25-26(36)2-1-3-27(25)37/h1-13,16H,14-15,17-18H2,(H,44,46)/t31-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintill...				US Patent US9458171 (2016) BindingDB Entry DOI: 10.7270/Q2NK3CZM
					More data for this Ligand-Target Pair