Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma [262-507]' and Ligand = 'BDBM268454'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma [262-507] (Homo sapiens (Human))	BDBM268454 (4-[3-(2-chloro-6-morpholino- benzoyl)imidazo[1,5-a...) Show SMILES OC(=O)c1ccc(cc1O)-c1nc(C(=O)c2c(Cl)cccc2N2CCOCC2)n2ccccc12 Show InChI InChI=1S/C25H20ClN3O5/c26-17-4-3-6-18(28-10-12-34-13-11-28)21(17)23(31)24-27-22(19-5-1-2-9-29(19)24)15-7-8-16(25(32)33)20(30)14-15/h1-9,14,30H,10-13H2,(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	25
Genentech, Inc. US Patent					Assay Description ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...				US Patent US9550771 (2017) BindingDB Entry DOI: 10.7270/Q2417036
					More data for this Ligand-Target Pair