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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma [262-507]' and Ligand = 'BDBM327480'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma [262-507]


(Homo sapiens (Human))		BDBM327480
PNG
(2-((S)-1-((4-fluorophenyl)sulfonyl)-6-(1,1,1,3,3,3...)
Show SMILES CC1(CNC(=O)C[C@@H]2CCc3cc(ccc3N2S(=O)(=O)c2ccc(F)cc2)C(O)(C(F)(F)F)C(F)(F)F)CNC(=O)O1 |r|
Show InChI InChI=1S/C25H24F7N3O6S/c1-22(13-34-21(37)41-22)12-33-20(36)11-17-6-2-14-10-15(23(38,24(27,28)29)25(30,31)32)3-9-19(14)35(17)42(39,40)18-7-4-16(26)5-8-18/h3-5,7-10,17,38H,2,6,11-13H2,1H3,(H,33,36)(H,34,37)/t17-,22?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 14.4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol using a scintillation proximity assay (SPA) ...

US Patent US9663469 (2017)


BindingDB Entry DOI: 10.7270/Q2ZS2ZN3
More data for this
Ligand-Target Pair