Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma [262-507]' and Ligand = 'BDBM327563'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma [262-507] (Homo sapiens (Human))	BDBM327563 (US9663469, 102 | US9663469, 120 | US9663469, 121) Show SMILES O[C@@H]1COC[C@H]1NC(=O)C[C@@H]1CCc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C24H23F7N2O6S/c25-15-3-6-17(7-4-15)40(37,38)33-16(10-21(35)32-18-11-39-12-20(18)34)5-1-13-9-14(2-8-19(13)33)22(36,23(26,27)28)24(29,30)31/h2-4,6-9,16,18,20,34,36H,1,5,10-12H2,(H,32,35)/t16-,18+,20+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol using a scintillation proximity assay (SPA) ...				US Patent US9663469 (2017) BindingDB Entry DOI: 10.7270/Q2ZS2ZN3
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma [262-507] (Homo sapiens (Human))	BDBM327563 (US9663469, 102 | US9663469, 120 | US9663469, 121) Show SMILES O[C@@H]1COC[C@H]1NC(=O)C[C@@H]1CCc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C24H23F7N2O6S/c25-15-3-6-17(7-4-15)40(37,38)33-16(10-21(35)32-18-11-39-12-20(18)34)5-1-13-9-14(2-8-19(13)33)22(36,23(26,27)28)24(29,30)31/h2-4,6-9,16,18,20,34,36H,1,5,10-12H2,(H,32,35)/t16-,18+,20+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol using a scintillation proximity assay (SPA) ...				US Patent US9663469 (2017) BindingDB Entry DOI: 10.7270/Q2ZS2ZN3
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma [262-507] (Homo sapiens (Human))	BDBM327563 (US9663469, 102 | US9663469, 120 | US9663469, 121) Show SMILES O[C@@H]1COC[C@H]1NC(=O)C[C@@H]1CCc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C24H23F7N2O6S/c25-15-3-6-17(7-4-15)40(37,38)33-16(10-21(35)32-18-11-39-12-20(18)34)5-1-13-9-14(2-8-19(13)33)22(36,23(26,27)28)24(29,30)31/h2-4,6-9,16,18,20,34,36H,1,5,10-12H2,(H,32,35)/t16-,18+,20+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol using a scintillation proximity assay (SPA) ...				US Patent US9663469 (2017) BindingDB Entry DOI: 10.7270/Q2ZS2ZN3
					More data for this Ligand-Target Pair