Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nucleotide-binding oligomerization domain-containing protein 2' and Ligand = 'BDBM4067'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM4067 (2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-meth...) Show SMILES CCN(CC)CCOc1ccc(Nc2ncc3cc(-c4ccccc4)c(=O)n(C)c3n2)cc1 Show InChI InChI=1S/C26H29N5O2/c1-4-31(5-2)15-16-33-22-13-11-21(12-14-22)28-26-27-18-20-17-23(19-9-7-6-8-10-19)25(32)30(3)24(20)29-26/h6-14,17-18H,4-5,15-16H2,1-3H3,(H,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113252 BindingDB Entry DOI: 10.7270/Q21Z4863
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