Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nucleotide-binding oligomerization domain-containing protein 2' and Ligand = 'BDBM50568942'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50568942 (CHEMBL4874031) Show SMILES CCN(CC)CCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(Cc4ccc(cc4)S(C)(=O)=O)c3n2)cc1 |(54.68,-6.89,;56.02,-6.11,;57.35,-6.88,;57.35,-8.42,;56.02,-9.19,;58.68,-6.11,;60.02,-6.88,;61.35,-6.11,;62.69,-6.88,;62.68,-8.43,;64.02,-9.2,;65.36,-8.43,;66.69,-9.19,;68.02,-8.42,;68.01,-6.89,;69.34,-6.11,;70.68,-6.88,;72.01,-6.11,;73.35,-6.89,;74.69,-6.12,;74.69,-4.59,;73.36,-3.82,;76.02,-3.82,;77.36,-4.6,;77.35,-6.14,;76.01,-6.9,;76.01,-8.44,;73.34,-8.43,;74.67,-9.21,;72,-9.2,;72,-10.74,;70.66,-11.5,;69.33,-10.72,;68,-11.48,;67.99,-13.02,;69.33,-13.8,;70.66,-13.03,;66.65,-13.78,;65.32,-13.01,;67.41,-15.11,;65.88,-15.11,;70.68,-8.42,;69.35,-9.19,;65.35,-6.88,;64.01,-6.11,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113252 BindingDB Entry DOI: 10.7270/Q21Z4863
					More data for this Ligand-Target Pair