Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM119562'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119562 (US8680275, 119) Show SMILES Clc1ccc2oc(nc2c1)N1C[C@@H]2CCN(C[C@H]12)C(=O)c1ccccc1-n1nccn1 |r| Show InChI InChI=1S/C22H19ClN6O2/c23-15-5-6-20-17(11-15)26-22(31-20)28-12-14-7-10-27(13-19(14)28)21(30)16-3-1-2-4-18(16)29-24-8-9-25-29/h1-6,8-9,11,14,19H,7,10,12-13H2/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17	-41.2	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
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