Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM119563'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119563 (US8680275, 120) Show SMILES Fc1cccc(c1C(=O)N1CC[C@H]2CN([C@H]2C1)c1nc2cc(Cl)ccc2o1)-n1nccn1 |r| Show InChI InChI=1S/C22H18ClFN6O2/c23-14-4-5-19-16(10-14)27-22(32-19)29-11-13-6-9-28(12-18(13)29)21(31)20-15(24)2-1-3-17(20)30-25-7-8-26-30/h1-5,7-8,10,13,18H,6,9,11-12H2/t13-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	26	-40.2	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
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