Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM119573'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119573 (US8680275, 130) Show SMILES Fc1ccc(c(c1)C(=O)N1CC[C@H]2CN([C@H]2C1)c1cc(ccn1)C(F)(F)F)-n1nccn1 |r| Show InChI InChI=1S/C21H18F4N6O/c22-15-1-2-17(31-27-6-7-28-31)16(10-15)20(32)29-8-4-13-11-30(18(13)12-29)19-9-14(3-5-26-19)21(23,24)25/h1-3,5-7,9-10,13,18H,4,8,11-12H2/t13-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	31	-39.8	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
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