Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM119594'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119594 (US8680275, 151) Show SMILES COc1ccc(c(c1)C(=O)N1CC[C@H]2CN([C@H]2C1)c1cc(C)cc(C)n1)-n1nccn1 |r| Show InChI InChI=1S/C23H26N6O2/c1-15-10-16(2)26-22(11-15)28-13-17-6-9-27(14-21(17)28)23(30)19-12-18(31-3)4-5-20(19)29-24-7-8-25-29/h4-5,7-8,10-12,17,21H,6,9,13-14H2,1-3H3/t17-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17	-41.2	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
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