Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM123361'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM123361 (US8742106, 5.1) Show SMILES C[C@H](NC(=O)COc1cc(C)c2c(nn(C)c2n1)-c1nc(C)cs1)c1ccc(C)cc1 |r| Show InChI InChI=1S/C23H25N5O2S/c1-13-6-8-17(9-7-13)16(4)25-18(29)11-30-19-10-14(2)20-21(23-24-15(3)12-31-23)27-28(5)22(20)26-19/h6-10,12,16H,11H2,1-5H3,(H,25,29)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	3	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...				US Patent US8742106 (2014) BindingDB Entry DOI: 10.7270/Q22V2DSW
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