Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM123372'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM123372 (US8742106, 6.8) Show SMILES C[C@H](NC(=O)COc1cc(C(F)F)c2c(nn(C)c2n1)C1CC1)c1ccc(C)cc1 |r| Show InChI InChI=1S/C22H24F2N4O2/c1-12-4-6-14(7-5-12)13(2)25-17(29)11-30-18-10-16(21(23)24)19-20(15-8-9-15)27-28(3)22(19)26-18/h4-7,10,13,15,21H,8-9,11H2,1-3H3,(H,25,29)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	32	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...				US Patent US8742106 (2014) BindingDB Entry DOI: 10.7270/Q22V2DSW
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM123372 (US8742106, 6.8) Show SMILES C[C@H](NC(=O)COc1cc(C(F)F)c2c(nn(C)c2n1)C1CC1)c1ccc(C)cc1 |r| Show InChI InChI=1S/C22H24F2N4O2/c1-12-4-6-14(7-5-12)13(2)25-17(29)11-30-18-10-16(21(23)24)19-20(15-8-9-15)27-28(3)22(19)26-18/h4-7,10,13,15,21H,8-9,11H2,1-3H3,(H,25,29)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	19	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...				US Patent US8742106 (2014) BindingDB Entry DOI: 10.7270/Q22V2DSW
					More data for this Ligand-Target Pair